FOLLICULAR FLUID-DERIVED EXOSOMAL MIR-143-3P/MIR-155-5P REGULATE FOLLICULAR DYSPLASIA BY MODULATING GLYCOLYSIS IN GRANULOSA CELLS IN POLYCYSTIC OVARY SYNDROME

Follicular fluid-derived exosomal miR-143-3p/miR-155-5p regulate follicular dysplasia by modulating glycolysis in granulosa cells in polycystic ovary syndrome

Abstract Objective Polycystic ovary syndrome (PCOS) is characterized by follicular dysplasia.An insufficient glycolysis-derived energy supply of granulosa cells (GCs) is an important cause of follicular dysplasia in PCOS.Follicular fluid (FF) exosomal microRNAs (miRNAs) have been proven read more to regulate the function of GCs.In this study, exoso

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Remodeling of the Actin Network Associated with the Non-Structural Protein 1 (NS1) of West Nile Virus and Formation of NS1-Containing Tunneling Nanotubes

The cellular response to the recombinant NS1 protein of West Nile virus (NS1WNV) was studied using three different cell types: Vero E6 simian epithelial cells, SH-SY5Y human neuroblastoma cells, and U-87MG human astrocytoma pentair hose cells.Cells were exposed to two different forms of NS1WNV: (i) the exogenous secreted form, sNS1WNV, added to the

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High-Power Ultraflat Near-Infrared Supercontinuum Generation Pumped by a Continuous Amplified Spontaneous Emission Source

A high-power ultraflat near-infrared supercontinuum (SC) is generated in a section of photonic crystal fiber (PCF) pumped by an amplified spontaneous emission (ASE) source instead of continuous-wave (CW) borstlist självhäftande and pulsed lasers.A low-power ASE seed at 1 μm is amplified to be 90.9 W by two fiber amplifiers and then emitted

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Theoretical and Experimental Methodology for Studying the Reduction of Evaporation in Open Mining Plant Reservoirs Using a Floating Photovoltaic System

Photovoltaic modules on floats in reservoirs, forming a floating photovoltaic (FPV) system, are proving to be relevant solutions for reducing evaporation and generating electricity.This paper presents a theoretical and experimental whole wheat phyllo dough methodology to evaluate the reduction of evaporation rates using FPV, applied at Hydro Parago

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